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KMID : 0370220110550050361
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Yakhak Hoeji
2011 Volume.55 No. 5 p.361 ~ p.366
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Analysis of Bioconversion Compositions from Fermented Bojungikki-tangs
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Kim Dong-Seon
Roh Joo-Hwan
Cho Chang-Won
Ma Jin-Yeul
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Abstract
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Traditional herbal medicinal preparation Bojungikki-tang (BJT) is well-known herbal medicine used as tonic. We fermented Bojungikki-tang using nine lactic acid bacteria strains and discovered two remarkably increased compositions from the fermented BJTs using HPLC/DAD analysis. HPLC/DAD-guided fractionation of the increased compositions followed by structure identification using NMR and MS identified liquiritigenin and isoliquiritigenin. These bioconversion compositions were quantitatively analyzed using HPLC-DAD. Liquiritigenin contents were highest in BJTs fermented with L. amylophilus (1.91 mg/g) and L. fermentum (1.89 mg/g), which were increased by 20-fold compared to BJT (0.09 mg/g). Isoliquiritigenin contents were highest in BJTs in fermented with L. plantarum (0.19 mg/g) and L. fermentum (0.19 mg/g), which were increased by 19-fold compared to BJT (0.01 mg/g).
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KEYWORD
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Bojungikki-tang, fermentation, herbal medicine, bioconversion, liquiritigenin, isoliquiritigenin
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